|
KMID : 1103720100620020149
|
|
Journal of the Korean Society of Radiology
2010 Volume.62 No. 2 p.149 ~ p.157
|
|
|
Detection of Intra-Abdominal Tumor Recurrence in Patients with Cholangiocarcinoma: Comparison of Contrast-Enhanced MDCT and 18F FDG-PET/CT
|
|
Kang Yang-Jun
Heo Suk-Hee
Kim Jin-Woong
Sin Sang-Su
Chang Nam-Kyu
Choi Song
Cho Chol-Kyoon
Bom Hee-Seung
Jeong Yong-Yeon
Kang Heoung-Keun
|
|
|
Abstract
|
|
|
Purpose: This study was designed to compare the diagnostic accuracy between the use of contrast-enhanced CT (CECT) and PET/CT for the detection of tumor recurrence in post-operative patients with cholangiocarcinoma during follow-up.
Materials and Methods : Twenty-five patients who had undergone abdominal CT and PET/CT examinations had clinical or imaging feature suspicious of recurrence. Ultimately, 16 patients (mean age, 65.1 years) were included in the study. The presence of recurrence was confirmed based on follow-up imaging (n = 10) or a biopsy (n = 6). Sensitivity, specificity and accuracy between the use of CECT and PET/CT were compared.
Results: Sixteen patients were found to have tumor recurrence. On a per patient basis, the sensitivity, specificity and accuracy for the use of CECT for tumor recurrence were 69%, 50% and 65%, respectively. The sensitivity, specificity and accuracy for the use of PET/CT for tumor recurrence were 100%, 75% and 95%, respectively. On a per lesion basis, the sensitivity, specificity and accuracy for the use of CECT for tumor recurrence were 73%, 50% and 70%, respectively. The sensitivity, specificity and accuracy for the use of PET/CT for tumor recurrence were 100%, 75% and 97%, respectively. PET/CT had significantly higher sensitivity and accuracy as compared to CT for the detection on a per lesion basis for recurred cholangiocarcinoma (p < 0.01).
Conclusion: PET/CT was more sensitive and accurate for the detection of recurrence of cholangiocarcinoma as compared to CECT. A PET/CT examination should be included in post-operative follow-up studies for the evaluation of recurred cholangiocarcinoma.
|
|
|
KEYWORD
|
|
|
Cholangiocarcinoma, Positron-Emission Tomography, Bile Ducts, Neoplasm Recurrence
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|